"What transforms Bruce Banner into the Hulk" NYT crossword answer is:
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When Bruce Banner is exposed to high levels of gamma radiation, it triggers a transformation that turns him into the Hulk. This transformation is caused by a combination of the radiation and Banner's own unique physiology, which allows him to absorb and channel the energy from the radiation into a powerful, green-skinned alter ego. This transformation is the source of the Hulk's incredible strength and durability, and it is what makes him one of the most powerful superheroes in the Marvel Universe.